STK4 Polyclonal Antibody

Applications

  • WB
  • ELISA

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bs-55209R
Product Name STK4 Polyclonal Antibody
Applications WB, ELISA
Specificity KO-Validated
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source Recombinant fusion protein containing a sequence corresponding to amino acids 303-487 of human STK4 (NP_006273.1).
Immunogen Range 303-487/487
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 6789
Swiss Prot Q13043
Subcellular location Cytoplasm, Nucleus
Synonyms KRS2;MST1;YSK3;STK4
Background The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.
Application Dilution
WB 1:300-1000
ELISA 1:500-1000