Overview |
bs-55226R |
YBX1 Polyclonal Antibody |
WB, IHC-P, IHC, IF |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human YBX1 (NP_004550.2). |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
4904 |
P67809 |
Cytoplasm, Nucleus, Secreted |
YBX1;BP-8;CBF-A;CSDA2;CSDB;DBPB;EFI-A;MDR-NF1;NSEP-1;NSEP1;YB-1;YB1 |
This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes. |
Application Dilution |
WB |
1:300-5000 |
IHC-P |
1:200-400 |
IHC |
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IF |
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