TSC2(Ser664) Polyclonal Antibody, PE-Cy5 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-5611R-PE-Cy5 |
| Product Name | TSC2(Ser664) Polyclonal Antibody, PE-Cy5 Conjugated |
| Applications |
FCM
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | PE-Cy5 |
| Host | Rabbit |
| Source | KLH conjugated synthetic phosphopeptide derived from human Tuberin around the phosphorylation site of Ser664 |
| Immunogen Range | 658-667/1807 |
| Modification Site | Ser664 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 7249 |
| Subcellular location | Cytoplasm, Cell membrane |
| Synonyms | TSC2phospho S664;FLJ43106; LAM; TSC2; TSC2_HUMAN; TSC4; Tuberin; Tuberous sclerosis 2 protein. |
| Background | Tuberin, or TSC2 (Tuberous sclerosis complex), is implicated as a tumor suppressor. It may function in vesicular transport, and may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between hamartin (TSC1) and tuberin may facilitate vesicular docking. It specifically stimulates the intrinsic GTPase activity of the Ras related protein RAP1A and RAB5, suggesting a possible mechanism for its role in regulating cellular growth. Mutations in tuberin lead to constitutive activation of RAP1A in tumors. At least three isoforms of Tuberin exist. |
| Application Dilution | |
| FCM | |
Frequently asked questions
Which applications is TSC2(Ser664) Polyclonal Antibody, PE-Cy5 Conjugated (bs-5611R-PE-Cy5) validated for, and at what dilution?
bs-5611R-PE-Cy5 is validated for FCM.
Which species does TSC2(Ser664) Polyclonal Antibody, PE-Cy5 Conjugated (bs-5611R-PE-Cy5) react with?
Tested reactivity: Human, Mouse, Rat.
How should bs-5611R-PE-Cy5 be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
What immunogen was used to raise TSC2(Ser664) Polyclonal Antibody, PE-Cy5 Conjugated (bs-5611R-PE-Cy5)?
KLH conjugated synthetic phosphopeptide derived from human Tuberin around the phosphorylation site of Ser664 Immunogen range: 658-667/1807.
What are the excitation and emission wavelengths of the PE-Cy5 conjugate (bs-5611R-PE-Cy5)?
PE-Cy5 on bs-5611R-PE-Cy5: excitation / emission 488nm/670nm.