MATK Polyclonal Antibody, FITC Conjugated
Applications
Predicted Reactivity
| Overview | |
| Catalog # | bs-5751R-FITC |
| Product Name | MATK Polyclonal Antibody, FITC Conjugated |
| Applications |
WB
IF(IHC-P)
IF(IHC-F)
IF(ICC)
|
| Predicted Reactivity | Human, Mouse, Rat, Dog, Cow, Pig, Horse |
| Specifications | |
| Conjugation | FITC |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human MATK |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 4145 |
| Subcellular location | Cytoplasm, Cell membrane |
| Synonyms | CHK; Csk homologous kinase; Csk type protein tyrosine kinase; CTK; Hematopoietic consensus tyrosine lacking kinase; HHYLTK; Hydroxyaryl protein kinase; HYL; HYL tyrosine kinase; HYLTK; Leukocyte carboxyl terminal src kinase related; Lsk; Megakaryocyte associated tyrosine kinase; Megakaryocyte associated tyrosine protein kinase; Protein kinase HYL; Tyrosine kinase MATK; Tyrosine protein kinase CTK; Tyrosylprotein kinase; MATK_HUMAN. |
| Background | The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. MATK is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. |
| Application Dilution | |
| WB | 1:300-5000 |
| IF(IHC-P) | 1:50-200 |
| IF(IHC-F) | 1:50-200 |
| IF(ICC) | 1:50-200 |
Frequently asked questions
Which applications is MATK Polyclonal Antibody, FITC Conjugated (bs-5751R-FITC) validated for, and at what dilution?
bs-5751R-FITC is validated for WB (1:300-5000); IF(IHC-P) (1:50-200); IF(IHC-F) (1:50-200); IF(ICC) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
How should bs-5751R-FITC be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise MATK Polyclonal Antibody, FITC Conjugated (bs-5751R-FITC)?
KLH conjugated synthetic peptide derived from human MATK
What are the excitation and emission wavelengths of the FITC conjugate (bs-5751R-FITC)?
FITC on bs-5751R-FITC: excitation / emission 494nm/518nm.