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EBP50 Polyclonal Antibody, HRP Conjugated

Applications

  • WB
  • ELISA
  • IHC-P
  • IHC-F

Predicted Reactivity

  • Human
  • Mouse
  • Rat
  • Cow
  • Pig
  • Chicken
  • Rabbit
Overview
Catalog # bs-5883R-HRP
Product Name EBP50 Polyclonal Antibody, HRP Conjugated
Applications WB, ELISA, IHC-P, IHC-F
Predicted Reactivity Human, Mouse, Rat, Cow, Pig, Chicken, Rabbit
Specifications
Conjugation HRP
Host Rabbit
Source KLH conjugated synthetic peptide derived from human EBP50/SLC9A3R1
Immunogen Range 281-358/358
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 9368
Subcellular location Cytoplasm, Cell membrane
Synonyms EBP 50; EBP50; Ezrin radixin moesin binding phosphoprotein 50; Ezrin-radixin-moesin-binding phosphoprotein 50; Na+/H+ exchange regulatory cofactor NHE RF; Na+/H+ exchange regulatory cofactor NHE-RF1; Na+/H+ exchange regulatory co factor; NHERF 1; NHERF; NHERF-1; NHERF1; NHRF1_HUMAN; NPHLOP2; Regulatory cofactor of Na+/H+ exchanger; SLC9A3R1; Sodium hydrogen exchanger regulatory factor 1; Sodium-hydrogen exchanger regulatory factor 1; Sodium/hydrogen exchanger regulatory factor 1; Solute carrier family 9 sodium/hydrogen exchanger member 3 regulator 1; Solute carrier family 9 sodium/hydrogen exchanger, isoform 3 regulatory factor 1; Solute carrier family 9 isoform 3 regulatory factor 1; Solute carrier family 9 isoform A3 regulatory factor 1; Solute carrier family 9 member 3 regulator 1.
Background Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May enhance Wnt signaling. May participate in HTR4 targeting to microvilli (By similarity). Interacts with MCC.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500