EMAP2 Polyclonal Antibody, Biotin Conjugated

Applications

  • WB
  • ELISA
  • IHC-P
  • IHC-F

Reactivity

  • Human

Predicted Reactivity

  • Mouse
  • Rat
  • Dog
  • Cow
  • Pig
  • Rabbit
Overview
Catalog # bs-5908R-Biotin
Product Name EMAP2 Polyclonal Antibody, Biotin Conjugated
Applications WB, ELISA, IHC-P, IHC-F
Reactivity Human
Predicted Reactivity Mouse, Rat, Dog, Cow, Pig, Rabbit
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human EMAP2
Immunogen Range 201-300/312
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 9255
Subcellular location Cytoplasm, Nucleus
Synonyms AIMP 1; Aimp1; AIMP1/p43; AIMP1_HUMAN ; Aminoacyl tRNA synthetase complex-interacting multunctional protein 1; ARS interacting multunctional protein 1; ARS-interacting multunctional protein 1; EMAP 2; EMAP-2; EMAP-II; EMAP II; EMAP2; EMAPII; Endothelial monocyte activating polypeptide 2; Endothelial Monocyte Activating Polypeptide; Endothelial monocyte-activating polypeptide 2; Endothelial monocyte-activating polypeptide II; Multisynthase complex auxiliary component p43; Multisynthetase complex auxiliary component p43; p43 antibody Scye 1; Scye1; Small Inducible Cytokine Subfamily E Member 1; Small inducible cytokine subfamily E, member 1 endothelial monocyte-activating.
Background Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500