EMAP2 Polyclonal Antibody, Biotin Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-5908R-Biotin |
| Product Name | EMAP2 Polyclonal Antibody, Biotin Conjugated |
| Applications |
WB
ELISA
IHC-P
IHC-F
|
| Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Dog, Cow, Pig, Rabbit |
| Specifications | |
| Conjugation | Biotin |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human EMAP2 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C for 12 months. |
| Target | |
| Gene ID | 9255 |
| Subcellular location | Cytoplasm, Nucleus |
| Synonyms | AIMP 1; Aimp1; AIMP1/p43; AIMP1_HUMAN ; Aminoacyl tRNA synthetase complex-interacting multunctional protein 1; ARS interacting multunctional protein 1; ARS-interacting multunctional protein 1; EMAP 2; EMAP-2; EMAP-II; EMAP II; EMAP2; EMAPII; Endothelial monocyte activating polypeptide 2; Endothelial Monocyte Activating Polypeptide; Endothelial monocyte-activating polypeptide 2; Endothelial monocyte-activating polypeptide II; Multisynthase complex auxiliary component p43; Multisynthetase complex auxiliary component p43; p43 antibody Scye 1; Scye1; Small Inducible Cytokine Subfamily E Member 1; Small inducible cytokine subfamily E, member 1 endothelial monocyte-activating. |
| Background | Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7. |
| Application Dilution | |
| WB | 1:300-5000 |
| ELISA | 1:500-1000 |
| IHC-P | 1:200-400 |
| IHC-F | 1:100-500 |
Frequently asked questions
Which applications is EMAP2 Polyclonal Antibody, Biotin Conjugated (bs-5908R-Biotin) validated for, and at what dilution?
bs-5908R-Biotin is validated for WB (1:300-5000); ELISA (1:500-1000); IHC-P (1:200-400); IHC-F (1:100-500). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does EMAP2 Polyclonal Antibody, Biotin Conjugated (bs-5908R-Biotin) react with?
Tested reactivity: Human. Predicted reactivity (expected from sequence homology but not yet tested): Mouse, Rat, Dog, Cow, Pig, Rabbit.
How should bs-5908R-Biotin be stored?
Store at -20C for 12 months. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise EMAP2 Polyclonal Antibody, Biotin Conjugated (bs-5908R-Biotin)?
KLH conjugated synthetic peptide derived from human EMAP2