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ACVRL1 Polyclonal Antibody, Cy3 Conjugated

Applications

  • WB
  • IF(IHC-P)

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bs-6020r-cy3-100ul
Product Name ACVRL1 Polyclonal Antibody, Cy3 Conjugated
Applications WB, IF(IHC-P)
Reactivity Human, Mouse, Rat
Specifications
Conjugation Cy3
Host Rabbit
Source KLH conjugated synthetic peptide derived from human ALK1
Immunogen Range 30-80/503
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 94
Swiss Prot P37023
Subcellular location Extracellular
Synonyms HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; TSR-I; ACVRLK1; Serine/threonine-protein kinase receptor R3; Activin receptor-like kinase 1; TGF-B superfamily receptor type I; ACVRL1
Background Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.
Application Dilution
WB 1:300-5000
IF(IHC-P) 1:50-200