CD32B(Tyr292) Polyclonal Antibody, Cy3 Conjugated

Applications

WB
FCM
IF(IHC-P)
IF(IHC-F)
IF(ICC)

Reactivity

Human
Mouse
Monkey

Predicted Reactivity

Rat
Dog
Sheep
Pig
Rabbit
Guinea Pig

Overview
Catalog #	bs-6031R-Cy3
Product Name	CD32B(Tyr292) Polyclonal Antibody, Cy3 Conjugated
Applications	WB, FCM, IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity	Human, Mouse, Monkey
Predicted Reactivity	Rat, Dog, Sheep, Pig, Rabbit, Guinea Pig
Specifications
Conjugation	Cy3
Host	Rabbit
Source	KLH conjugated synthetic phosphopeptide derived from human CD32B around the phosphorylation site of Tyr292.
Modification Site	Tyr292
Clonality	Polyclonal
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition	Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID	2213
Swiss Prot	P31994
Subcellular location	Cell membrane
Synonyms	CD32; FCG2; CD32B; FCGR2; IGFR2; Low affinity immunoglobulin gamma Fc region receptor II-b; IgG Fc receptor II-b; CDw32; Fc-gamma RII-b; Fc-gamma-RIIb; FcRII-b; FCGR2B
Background	Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
Application Dilution
WB	1:300-5000
FCM	1:20-100
IF(IHC-P)	1:50-200
IF(IHC-F)	1:50-200
IF(ICC)	1:50-200

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