| Overview |
| bs-6107R |
| HLTF Polyclonal Antibody |
| ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC) |
| Human, Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit |
| Specifications |
| Unconjugated |
| Rabbit |
| KLH conjugated synthetic peptide derived from human HLTF. |
| 201-300/1009 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Target |
| 6596 |
| Cytoplasm, Nucleus |
| DNA-binding protein/plasminogen activator inhibitor 1 regulator; Helicase like transcription factor; Helicase-like transcription factor; HIP116; HIP116A; HLTF 1; HLTF; HLTF_HUMAN; HLTF1; p113; RING finger protein 80; RNF80; SMARC A3; SMARCA 3; SMARCA3; SNF2-like 3; SNF2L3; Sucrose nonfermenting protein 2 like 3; Sucrose nonfermenting protein 2-like 3; SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3; ZBU 1; ZBU1. |
| Has both helicasee and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity; This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination of chromatin-bound PCNA. |
| Application Dilution |
| ELISA |
1:500-1000 |
| IHC-P |
1:200-400 |
| IHC-F |
1:100-500 |
| IF(IHC-P) |
1:50-200 |
| IF(IHC-F) |
1:50-200 |
| IF(ICC) |
1:50-200 |
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