EMP2 Polyclonal Antibody, PE-Cy7 Conjugated
Applications
Predicted Reactivity
| Overview | |
| Catalog # | bs-6264R-PE-Cy7-100uL |
| Product Name | EMP2 Polyclonal Antibody, PE-Cy7 Conjugated |
| Applications |
WB
|
| Predicted Reactivity | Human, Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit |
| Specifications | |
| Conjugation | PE-Cy7 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human EMP2 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 2013 |
| Subcellular location | Cell membrane |
| Synonyms | EMP-2; EMP2; EMP2_HUMAN; Epithelial membrane protein 2; Protein XMP. |
| Background | EMP-2 is a 167 amino acid multi-pass membrane protein that contains four-transmembrane domains and belongs to the GAS3/PMP22 (growth arrest-specific-3/peripheral myelin protein-22) family. Localized to lipid raft domains in the plasma membrane, EMP-2 regulates the expression of several target proteins and is necessary for blastocyst implantation in the uterine endometrium. Specifically, EMP-2 mediates blastocyst implantation by controlling the cell membrane expression of MHC and glycosylphosphatidylinositol-anchored proteins, as well as Integrins and caveolin-1. In adult tissues, EMP-2 is expressed in heart, lung, ovary and intestine, while fetal expression is highest in kidney, brain and liver. Overexpression of EMP-2 is associated with endometrial adenocarcinoma, suggesting a possible role for EMP-2 in tumorigenesis. |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is EMP2 Polyclonal Antibody, PE-Cy7 Conjugated (bs-6264R-PE-Cy7) validated for, and at what dilution?
bs-6264R-PE-Cy7 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
How should bs-6264R-PE-Cy7 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise EMP2 Polyclonal Antibody, PE-Cy7 Conjugated (bs-6264R-PE-Cy7)?
KLH conjugated synthetic peptide derived from human EMP2
What are the excitation and emission wavelengths of the PE-Cy7 conjugate (bs-6264R-PE-Cy7)?
PE-Cy7 on bs-6264R-PE-Cy7: excitation / emission 488nm/780nm.