Overview |
bs-6313R-BF750 |
4 Hydroxynonenal Polyclonal Antibody, AbBy Fluor® 750 Conjugated |
WB, IF(IHC-P) |
Mouse, Rat, Others, Monkey |
Specifications |
AbBy Fluor® 750 |
Rabbit |
KLH-conjugated 4-hydroxynonenal |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
Cytoplasm |
4-Hydroxy-2-Nonenal; 4Hydroxynonenal; 4-Hydroxynonenal; 4 HNE; 4HNE; 4-HNE; E-4-Hydroxynonenal-dimethylacetal, 4-HNE-DMA. |
Aldehydic products of lipid peroxidation, such as 4 hydroxynonenal (4 HNE), have been implicated in the etiology of pathological changes under oxidative stress as a key mediator of oxidative stress induced cell death. It is a stable product of lipid peroxidation, is proarrhythmic and may contribute to the cytotoxic effects of oxidative stress
4-HNE has been hypothesized to play a key role in cell signal transduction, in a variety of pathways from cell cycle events to cellular adhesion. |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-P) |
1:50-200 |