| Overview |
| bs-6335R-Biotin |
| ALOX15B Polyclonal Antibody, Biotin Conjugated |
| IHC-P, IHC-F |
| Rat |
| Human, Mouse, Cow, Pig, Horse, Rabbit |
| Specifications |
| Biotin |
| Rabbit |
| KLH conjugated synthetic peptide derived from human ALOX15B/15 Lipoxygenase 2 |
| 13-110/676 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Target |
| 247 |
| O15296 |
| Cytoplasm |
| 15-LOX-2; Arachidonate 15-lipoxygenase B; 15-LOX-B; 15-lipoxygenase 2; Arachidonate 15-lipoxygenase type II; Linoleate 13-lipoxygenase 15-LOb; ALOX15B |
| Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid/(15S)-HPETE. Also acts on linoleic acid to produce 13-hydroxyoctadecadienoic acid/13-HPODE. Has no detectable 8S-lipoxygenase activity but reacts with (8S)-HPETE to produce (8S,15S)-diHPETE. May regulate progression through the cell cycle and cell proliferation. May also regulate cytokine secretion by macrophages and therefore play a role in the immune response. May also regulate macrophage differentiation into proatherogenic foam cells. |
| Application Dilution |
| IHC-P |
1:200-400 |
| IHC-F |
1:100-500 |
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