PEN2 Polyclonal Antibody

Applications

  • IHC-P
  • IF(IHC-P)

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bs-6456R
Product Name PEN2 Polyclonal Antibody
Applications IHC-P, IF(IHC-P)
Specificity Belongs to the PEN-2 family
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human PEN2
Immunogen Range 1-50/101
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Target
Gene ID 55851
Swiss Prot Q9NZ42
Subcellular location Lumenal
Synonyms PEN2; PEN-2; MDS033; MSTP064; Gamma-secretase subunit PEN-2; Presenilin enhancer protein 2; PSENEN
Background Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.
Application Dilution
IHC-P 1:200-400
IF(IHC-P) 1:50-200