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PEN2 Polyclonal Antibody, HRP Conjugated

Applications

  • WB
  • ELISA
  • IHC-P
  • IHC-F

Reactivity

  • Mouse
  • Rat

Predicted Reactivity

  • Human
  • Dog
  • Cow
  • Pig
  • Horse
  • Rabbit
Overview
Catalog # bs-6456R-HRP-100uL
Product Name PEN2 Polyclonal Antibody, HRP Conjugated
Applications
WB ELISA IHC-P IHC-F
Specificity Belongs to the PEN-2 family
Reactivity Mouse, Rat
Predicted Reactivity Human, Dog, Cow, Pig, Horse, Rabbit
Specifications
Conjugation HRP
Host Rabbit
Source KLH conjugated synthetic peptide derived from human PEN2
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 55851
Swiss Prot Q9NZ42
Subcellular location Cytoplasm, Cell membrane
Synonyms PEN2; PEN-2; MDS033; MSTP064; Gamma-secretase subunit PEN-2; Presenilin enhancer protein 2; PSENEN
Background Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500

Frequently asked questions

Which applications is PEN2 Polyclonal Antibody, HRP Conjugated (bs-6456R-HRP) validated for, and at what dilution?

bs-6456R-HRP is validated for WB (1:300-5000); ELISA (1:500-1000); IHC-P (1:200-400); IHC-F (1:100-500). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does PEN2 Polyclonal Antibody, HRP Conjugated (bs-6456R-HRP) react with?

Tested reactivity: Mouse, Rat. Predicted reactivity (expected from sequence homology but not yet tested): Human, Dog, Cow, Pig, Horse, Rabbit.

How should bs-6456R-HRP be stored?

Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise PEN2 Polyclonal Antibody, HRP Conjugated (bs-6456R-HRP)?

KLH conjugated synthetic peptide derived from human PEN2