NALP3/CIAS1 Polyclonal Antibody, APC Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-6655R-APC-100uL |
| Product Name | NALP3/CIAS1 Polyclonal Antibody, APC Conjugated |
| Applications |
WB
IF
|
| Reactivity | Human, Mouse, Rat, Dog |
| Specifications | |
| Conjugation | APC |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human Cryopyrin |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 114548 |
| Subcellular location | Cytoplasm |
| Synonyms | NACHT, LRR and PYD domains-containing protein 3; Angiotensin/vasopressin receptor AII/AVP-like; Caterpiller protein 1.1; CLR1.1; Cold autoinflammatory syndrome 1 protein; Cryopyrin; PYRIN-containing APAF1-like protein 1; NLRP3; C1orf7; CIAS1; NALP3; PYPAF1 |
| Background | May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18. |
| Application Dilution | |
| WB | FCM1:20-100 |
| IF | |
Frequently asked questions
Which applications is NALP3/CIAS1 Polyclonal Antibody, APC Conjugated (bs-6655R-APC) validated for, and at what dilution?
bs-6655R-APC is validated for FCM (1:20-100). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does NALP3/CIAS1 Polyclonal Antibody, APC Conjugated (bs-6655R-APC) react with?
Tested reactivity: Human, Mouse, Rat, Dog.
How should bs-6655R-APC be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise NALP3/CIAS1 Polyclonal Antibody, APC Conjugated (bs-6655R-APC)?
KLH conjugated synthetic peptide derived from human Cryopyrin
What are the excitation and emission wavelengths of the APC conjugate (bs-6655R-APC)?
APC on bs-6655R-APC: excitation / emission 650nm/660nm.