NALP3/CIAS1 Polyclonal Antibody, PE-Cy7 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-6655R-PE-Cy7-100uL |
| Product Name | NALP3/CIAS1 Polyclonal Antibody, PE-Cy7 Conjugated |
| Applications |
WB
|
| Reactivity | Human, Mouse, Rat, Dog |
| Specifications | |
| Conjugation | PE-Cy7 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human Cryopyrin |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 114548 |
| Subcellular location | Cytoplasm |
| Synonyms | NACHT, LRR and PYD domains-containing protein 3; Angiotensin/vasopressin receptor AII/AVP-like; Caterpiller protein 1.1; CLR1.1; Cold autoinflammatory syndrome 1 protein; Cryopyrin; PYRIN-containing APAF1-like protein 1; NLRP3; C1orf7; CIAS1; NALP3; PYPAF1 |
| Background | May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18. |
| Application Dilution | |
| WB | FCM1:20-100 |
Frequently asked questions
Which applications is NALP3/CIAS1 Polyclonal Antibody, PE-Cy7 Conjugated (bs-6655R-PE-Cy7) validated for, and at what dilution?
bs-6655R-PE-Cy7 is validated for FCM (1:20-100). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does NALP3/CIAS1 Polyclonal Antibody, PE-Cy7 Conjugated (bs-6655R-PE-Cy7) react with?
Tested reactivity: Human, Mouse, Rat, Dog.
How should bs-6655R-PE-Cy7 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise NALP3/CIAS1 Polyclonal Antibody, PE-Cy7 Conjugated (bs-6655R-PE-Cy7)?
KLH conjugated synthetic peptide derived from human Cryopyrin
What are the excitation and emission wavelengths of the PE-Cy7 conjugate (bs-6655R-PE-Cy7)?
PE-Cy7 on bs-6655R-PE-Cy7: excitation / emission 488nm/780nm.