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AQP0 Polyclonal Antibody, Biotin Conjugated

Applications

  • ELISA
  • IHC-P
  • IHC-F

Predicted Reactivity

  • Human
  • Mouse
  • Rat
  • Cow
  • Sheep
  • Pig
  • Horse
  • Chicken
  • Rabbit
  • Guinea Pig
Overview
Catalog # bs-6661R-Biotin
Product Name AQP0 Polyclonal Antibody, Biotin Conjugated
Applications ELISA, IHC-P, IHC-F
Predicted Reactivity Human, Mouse, Rat, Cow, Sheep, Pig, Horse, Chicken, Rabbit, Guinea Pig
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human AQP0
Immunogen Range 21-120/263
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 4284
Swiss Prot P30301
Subcellular location Cell membrane
Synonyms AQP0; LIM1; MP26; MIP26; CTRCT15; Lens fiber major intrinsic protein; Aquaporin-0; MIP
Background Water channel (PubMed:24120416). Channel activity is down-regulated by CALM when cytoplasmic Ca(2+) levels are increased. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core (By similarity). Plays a role in cell-to-cell adhesion and facilitates gap junction coupling (PubMed:24120416).
Application Dilution
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500