Factor B Polyclonal Antibody, Biotin Conjugated

Applications

  • WB
  • ELISA
  • IHC-P

Reactivity

  • Mouse
  • Rat
Overview
Catalog # bs-6949R-Biotin
Product Name Factor B Polyclonal Antibody, Biotin Conjugated
Applications WB, ELISA, IHC-P
Reactivity Mouse, Rat
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Complement factor-B Bb fragment
Immunogen Range 301-400/764
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 629
Swiss Prot P00751
Subcellular location Secreted
Synonyms BF; FB; BFD; GBG; CFAB; CFBD; PBF2; AHUS4; FBI12; H2-Bf; ARMD14; Complement factor B; C3/C5 convertase; Glycine-rich beta glycoprotein; Properdin factor B; CFB
Background Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400