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ASMT Polyclonal Antibody, Biotin Conjugated

Applications

  • WB
  • ELISA
  • IHC-P
  • IHC-F

Reactivity

  • Rat
  • Sheep
  • Others

Predicted Reactivity

  • Human
  • Mouse
  • Dog
  • Cow
  • Horse
Overview
Catalog # bs-6961R-Biotin
Product Name ASMT Polyclonal Antibody, Biotin Conjugated
Applications WB, ELISA, IHC-P, IHC-F
Reactivity Rat, Sheep, Others
Predicted Reactivity Human, Mouse, Dog, Cow, Horse
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Acetylserotonin O-methyltransferase (ASMT)
Immunogen Range 241-345/345
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 438
Swiss Prot P46597
Subcellular location Cytoplasm
Synonyms Acetylserotonin O-methyltransferase; ASMT; ASMTY; HIOMT; HIOMTY; Hydroxyindole O-methyltransferase.
Background This gene belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland. Alternatively spliced transcript variants have been noted for this gene. Isoform 1 catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). Isoform 2 and isoform 3 lack enzyme activity
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500