Ribosomal S6 kinase 2 Antibody
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-70249r |
| Product Name | Ribosomal S6 kinase 2 Antibody |
| Applications |
WB
|
| Specificity | Specific for endogenous levels of the ~90 kDa RSK2 protein. |
| Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Dog, Bovine, Chicken |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Synthetic peptide corresponding to amino acid residues from the C-terminal region on mouse ribosomal S6 kinase 2, conjugated to keyhole limpet hemocyanin (KLH). |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | Antigen Affinity purification from Pooled whole antiserum |
| Storage Buffer | 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol. |
| Storage Condition | Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C. |
| Target | |
| Gene ID | 20112 |
| Swiss Prot | Q9WUT3 |
| Synonyms | 90 kDa ribosomal protein S6 kinase 2 antibody, HU 2 antibody, KS6A2_HUMAN antibody, MAP kinase activated protein kinase 1c antibody, MAP kinase-activated protein kinase 1c antibody, MAPK-activated protein kinase 1c antibody, MAPKAP kinase 1c antibody, MAPKAPK-1c antibody, MAPKAPK1C antibody, Mitogen.activated protein kinase-activated protein kinase 1C antibody, p90 RSK3 antibody, p90-RSK 2 antibody, p90RSK2 antibody, pp90RSK3 antibody, Ribosomal protein S6 kinase alpha-2 antibody, ribosomal protein S6 kinase 90kDa polypeptide 2 antibody, Ribosomal S6 kinase 3 antibody, RPS6KA2 antibody, RSK3 antibody, RSK 3 antibody, RSK antibody, RSK-3 antibody, S6K alpha antibody, S6K alpha 2 antibody, S6K-alpha-2 antibody |
| Background | The p90 ribosomal S6 kinases (RSK)1–4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin–Lowry syndrome, which is characterized by mental retardation and growth deficits (Hanauer and Young, 2002). Recent work suggests that RSK2 exerts a tonic regulation on G-protein coupled signaling (Sheffler et al., 2006). |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is Ribosomal S6 kinase 2 Antibody (bs-70249R) validated for, and at what dilution?
bs-70249R is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does Ribosomal S6 kinase 2 Antibody (bs-70249R) react with?
Tested reactivity: Human. Predicted reactivity (expected from sequence homology but not yet tested): Mouse, Rat, Dog, Bovine, Chicken.
How should bs-70249R be stored?
Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C. Storage buffer: 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
What immunogen was used to raise Ribosomal S6 kinase 2 Antibody (bs-70249R)?
Synthetic peptide corresponding to amino acid residues from the C-terminal region on mouse ribosomal S6 kinase 2, conjugated to keyhole limpet hemocyanin (KLH).