ARHGEF18 Polyclonal Antibody, APC Conjugated
Applications
Predicted Reactivity
| Overview | |
| Catalog # | bs-7144R-APC-100uL |
| Product Name | ARHGEF18 Polyclonal Antibody, APC Conjugated |
| Applications |
IF(IHC-P)
IF(IHC-F)
IF(ICC)
|
| Predicted Reactivity | Human, Mouse, Rat, Dog, Cow, Sheep, Pig, Chicken |
| Specifications | |
| Conjugation | APC |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human ARHGEF18/p114RhoGEF |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 23370 |
| Subcellular location | Cytoplasm |
| Synonyms | 114 kDa Rho specic guanine nucleotide exchange factor; ARHGEF 18; ARHGEF18; KIAA0521; MGC15913; p114 Rho GEF; p114-Rho-GEF; Rho specic guanine nucleotide exchange factor p114; Rho-specic guanine nucleotide exchange factor p114; Rho/Rac guanine nucleotide exchange factor GEF 18; Rho/Rac guanine nucleotide exchange factor 18; SA RhoGEF; Septin associated RhoGEF; ARHGI_HUMAN. |
| Background | Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]. |
| Application Dilution | |
| IF(IHC-P) | 1:50-200 |
| IF(IHC-F) | 1:50-200 |
| IF(ICC) | 1:50-200 |
Frequently asked questions
Which applications is ARHGEF18 Polyclonal Antibody, APC Conjugated (bs-7144R-APC) validated for, and at what dilution?
bs-7144R-APC is validated for IF(IHC-P) (1:50-200); IF(IHC-F) (1:50-200); IF(ICC) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
How should bs-7144R-APC be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise ARHGEF18 Polyclonal Antibody, APC Conjugated (bs-7144R-APC)?
KLH conjugated synthetic peptide derived from human ARHGEF18/p114RhoGEF
What are the excitation and emission wavelengths of the APC conjugate (bs-7144R-APC)?
APC on bs-7144R-APC: excitation / emission 650nm/660nm.