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KLHL20 Polyclonal Antibody, Biotin Conjugated

Applications

  • ELISA
  • IHC-P
  • IHC-F

Reactivity

  • Rat

Predicted Reactivity

  • Human
  • Mouse
  • Cow
  • Sheep
  • Chicken
  • Rabbit
Overview
Catalog # bs-7515R-Biotin
Product Name KLHL20 Polyclonal Antibody, Biotin Conjugated
Applications ELISA, IHC-P, IHC-F
Reactivity Rat
Predicted Reactivity Human, Mouse, Cow, Sheep, Chicken, Rabbit
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human KLHL20
Immunogen Range 13-100/609
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 27252
Subcellular location Cytoplasm, Nucleus
Synonyms Kelch like ECT2 interacting protein; Kelch like protein 20; Kelch like protein X; Kelch mot containing protein; Kelch-like ECT2-interacting protein; Kelch-like protein 20; Kelch-like protein X; KHLHX; KLEIP; KLH20CHUMAN; KLHL20; KLHLX; RP3-383J4.3.
Background Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in interferon response. The BCR(KLHL20) E3 ubiquitin ligase complex mediates the ubiquitination of DAPK1, leading to its degradation by the proteasome, thereby acting as a negative regulator of apoptosis. Also acts as a regulator of endothelial migration during angiogenesis by controlling the activation of Rho GTPases.
Application Dilution
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500