Narciclasine
| Overview | |
| Catalog # | bs-75270c-500ug |
| Product Name | Narciclasine |
| Specifications | |
| Storage Buffer | Powder |
| Storage Condition | Stable for 2 years after receipt when stored at -20°C. |
| Target | |
| Product Information | CAS Number: 29477-83-6 Molecular formula: C14H13NO7 Molecular weight: 307.3 Purity: >98% (HPLC) Appearance: Pale grey powder. Solubility: Soluble in DMSO (30mg/ml). InChiKey: LZAZURSABQIKGB-AEKGRLRDSA-N SMILES: OC1=C(C(N[C@]2([H])C3=C[C@H](O)[C@@H](O)[C@H]2O)=O)C3=CC4=C1OCO4 |
| Description | Plant growth modulator/inhibitor. Anticancer agent. Exhibits antiproliferative and pro-apoptotic effects in carcinoma cells and displays cytotoxic activity against a panel of 60 cancer cell lines. Shown to promote autophagy-induced apoptosis and to slow cell cycle progression. Inhibits protein synthesis by interacting with the 60S ribosome subunit. Regulates the Rho/ROCK/LIM kinase/cofilin pathway. Stimulates RhoA activation and induces actin polymerization. Anti-obesity agent. Attenuates diet-induced obesity (DIO) in mice by promoting oxidative metabolism in skeletal muscle and energy expenditure. Anti-inflammatory agent suppressing NF-kappaB-dependent gene transcription. Antiviral agent in vitro. Antifungal agent. Shown to inhibit amyloid plaque formation in an Alzheimer's disease model. |