Ac-Pro-Ala-Leu-AMC
| Overview | |
| Catalog # | bs-75319c-1mg |
| Product Name | Ac-Pro-Ala-Leu-AMC |
| Specifications | |
| Storage Buffer | Powder |
| Storage Condition | Stable for 1 year after receipt when stored at -20°C. |
| Target | |
| Product Information | CAS Number: 1431362-79-6 Molecular formula: C26H34N4O6 Molecular weight: 498.6 Purity: >97% Appearance: Lyophilized powder. Solubility: Soluble in DMSO. InChiKey: BWJPVHDZSJFFDM-NDXORKPFSA-N SMILES: O=C(C)N1CCC[C@H]1C(N[C@@H](C)C(N[C@@H](CC(C)C)C(NC2 =CC=C(C(C)=CC(O3)=O)C3=C2)=O)=O)=O |
| Description | Ac-PAL-AMC is a fluorogenic peptide substrate for measuring caspase-like activity of the immunoproteasome. Hydrolysis of this substrate by the beta1i/LMP2-subunit of the immunoproteasome is monitored by observing fluorescence at an Excitation wavelength of 345nm and Emission at 445nm. This substrate is specific to the immunoproteasome and is not hydrolyzed efficiently by the constitutive proteasome. |
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