PGC1 alpha + beta Polyclonal Antibody, PE-Cy5 Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-7535R-PE-Cy5-100uL |
| Product Name | PGC1 alpha + beta Polyclonal Antibody, PE-Cy5 Conjugated |
| Applications |
WB
FCM
|
| Reactivity | Human, Rat |
| Predicted Reactivity | Mouse, Dog, Cow, Pig, Horse, Rabbit |
| Specifications | |
| Conjugation | PE-Cy5 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human PGC1 alpha |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 10891 |
| Swiss Prot | Q9UBK2 |
| Subcellular location | Nucleus |
| Synonyms | LEM6; Ligand effect modulator 6; PERC; Peroxisome prolerative activated receptor, gamma, coactivator 1 alpha; Peroxisome prolerative activated receptor, gamma, coactivator 1; Peroxisome prolerator activated receptor gamma coactivator 1 alpha; peroxisome prolerator-activated receptor gamma coactivator 1 beta; Peroxisome prolerator-activated receptor gamma coactivator 1-alpha; Peroxisome prolerator-activated receptor gamma coactivator 1-beta; peroxisome prolerator-activated receptor gamma, coactivator 1 beta; PGC 1 alpha; PGC 1 alpha; PGC 1v; PGC-1beta; PGC-1-alpha; PGC-1-beta; PGC-1-related estrogen receptor alpha coactivator; PGC1; PGC1alpha; PGC1A; PGC1v; PPAR gamma coactivator 1 alpha; PPAR gamma coactivator 1 alpha 3 ligand effect modulator 6; PPAR gamma coactivator 1; PPAR gamma coactivator variant form; PPAR gamma coactivator-1beta; PPAR-gamma coactivator 1-alpha; PPAR-gamma coactivator 1-beta; PPARGC 1 alpha; PPARGC-1-alpha; PPARGC-1-beta; PPARGC1; PPARGC1A; Ppargc1b; PRGC1_HUMAN; PRGC2_HUMAN. |
| Background | The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq]. |
| Application Dilution | |
| WB | 1:300-5000 |
| FCM | 1:20-100 |
Frequently asked questions
Which applications is PGC1 alpha + beta Polyclonal Antibody, PE-Cy5 Conjugated (bs-7535R-PE-Cy5) validated for, and at what dilution?
bs-7535R-PE-Cy5 is validated for WB (1:300-5000); FCM (1:20-100). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does PGC1 alpha + beta Polyclonal Antibody, PE-Cy5 Conjugated (bs-7535R-PE-Cy5) react with?
Tested reactivity: Human, Rat. Predicted reactivity (expected from sequence homology but not yet tested): Mouse, Dog, Cow, Pig, Horse, Rabbit.
How should bs-7535R-PE-Cy5 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise PGC1 alpha + beta Polyclonal Antibody, PE-Cy5 Conjugated (bs-7535R-PE-Cy5)?
KLH conjugated synthetic peptide derived from human PGC1 alpha
What are the excitation and emission wavelengths of the PE-Cy5 conjugate (bs-7535R-PE-Cy5)?
PE-Cy5 on bs-7535R-PE-Cy5: excitation / emission 488nm/670nm.