6BIO

Overview
Catalog #	bs-75386c-1mg
Product Name	6BIO
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 667463-62-9 Molecular formula: C16H10BrN3O2 Molecular weight: 356.2 Purity: >98% (NMR) Appearance: Dark red solid. Solubility: Soluble in DMSO. InChiKey: DDLZLOKCJHBUHD-WAVHTBQISA-N SMILES: O\N=C1\C(\NC2=CC=CC=C\12)=C1\C(=O)NC2=C1C=CC(Br)=C2
Description	Phosphoinositide-dependent kinase 1 (PDK1) inhibitor. Potent, reversible and ATP-competitive glycogen synthase kinase-3alpha/beta (GSK-3alpha/beta) inhibitor. JAK/STAT3 signaling inhibitor. Apoptosis inducer. Potent antiproliferative agent in malignant lymphoid cell. Antimetastatic agent. Potent chemosensitizing agent fighting TRAIL resistant cancer cells.