Tripolin A

Overview
Catalog #	bs-75445c-1mg
Product Name	Tripolin A
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.
Target
Product Information	CAS Number: 1148118-92-6 Molecular formula: C15H11NO3 Molecular weight: 253.3 Purity: >98% (HPLC, NMR) Appearance: Yellow solid. Solubility: Soluble in DMSO (at least 10 mg/ml). InChiKey: OMKSBDLWMROKNU-WQLSENKSSA-N SMILES: OC1=CC=C(O)C(\C=C2/C(=O)NC3=C2C=CC=C3)=C1
Description	Specific non-ATP competitive Aurora A kinase inhibitor [1]. Does not significantly inhibit Aurora B kinase in mammalian cells. Reduces localization of pAurora A on spindle microtubules (MTs), affects centrosome integrity, spindle formation and length and MT dynamics in interphase [1].