Empagliflozin

Overview
Catalog #	bs-75519c-10mg
Product Name	Empagliflozin
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 3 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 864070-44-0 Molecular formula: C23H27ClO7 Molecular weight: 450.9 Purity: >98% (HPLC) Appearance: White solid. Solubility: Soluble in DMSO. Slightly soluble in water or ethanol. InChiKey: OBWASQILIWPZMG-QZMOQZSNSA-N SMILES: OCC1O[C@H](C(O)[C@@H](O)[C@@H]1O)C1=CC(CC2=CC=C(O[C@H]3CCOC3)C=C2)=C(Cl)C=C1
Description	Antidiabetic agent. Potent and selective sodium glucose co-transporter 2 (SGLT-2) inhibitor. >300-fold selectivity over SGLT-1, 4, 5 and 6. SGLT-2 is found almost exclusively in the proximal tubules of nephronic components in kidneys. Inhibition of SGLT-2 reduces blood glucose by blocking renal glucose reabsorption and thereby increasing urinary glucose excretion (UGE). Shown to preserves beta cell mass and restore glucose homeostasis.