TG007
| Overview | |
| Catalog # | bs-75555c-5mg |
| Product Name | TG007 |
| Specifications | |
| Storage Buffer | Solid |
| Storage Condition | Stable for 2 years after receipt when stored at -20°C. |
| Target | |
| Product Information | CAS Number: 719277-30-2 Molecular formula: C14H15NO3S Molecular weight: 277.3 Purity: >98% (HPLC) Appearance: White to off-white solid. Solubility: Soluble in DMSO (10mg/ml). InChiKey: RLEOCVDWLAYGRX-AUWJEWJLSA-N SMILES: O=C(C)/C=C1SC2=CC=C(OC(C)=O)C=C2N\1CC |
| Description | Cell permeable ATP-competitive DYRK1A and DYRK1B inhibitor. Inhibits phosphorylation of Tau-protein and rescues repressed calcineurin/NFAT signaling. Recovers Xenopus embryos from head malformation induced by DYRK1A overexpression in vivo. |