| Overview |
| bs-7562R-HRP |
| TIRAP(Tyr86) Polyclonal Antibody, HRP Conjugated |
| WB, ELISA, IHC-P, IHC-F |
| Human |
| Mouse, Dog, Cow, Pig, Horse, Guinea Pig |
| Specifications |
| HRP |
| Rabbit |
| KLH conjugated synthetic acetylpeptide derived from human TIRAP around phosphorylation site of Tyr86 [KD(p-Y)DV] |
| Tyr86 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 114609 |
| P58753 |
| Cytoplasm |
| Mal; wyatt; BACTS1; MyD88-2; Toll/interleukin-1 receptor domain-containing adapter protein; TIR domain-containing adapter protein; Adaptor protein Wyatt; MyD88 adapter-like protein; TIRAP |
| Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6. |
| Application Dilution |
| WB |
1:300-5000 |
| ELISA |
1:500-1000 |
| IHC-P |
1:200-400 |
| IHC-F |
1:100-500 |
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