Simocyclinone D8
| Overview | |
| Catalog # | bs-75729c-1mg |
| Product Name | Simocyclinone D8 |
| Specifications | |
| Storage Buffer | Powder |
| Storage Condition | Stable for 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C. |
| Target | |
| Product Information | CAS Number: 301845-97-6 Molecular formula: C46H42ClNO18 Molecular weight: 932.3 Purity: >97% (HPLC) Appearance: Yellow powder. Solubility: Soluble in DMSO, methanol, acetone, dichloromethane or ethyl acetate. InChiKey: PLEGMCYXNQPJNV-TYXWGSLYSA-N SMILES: C[C@H]1O[C@H](C[C@@H](OC(=O)\C=C\C=C\C=C\C=C\C(=O)NC2=C(O)C3=C(OC2=O)C(Cl)=C(O)C=C3)[C@@H]1OC(C)=O)C1=C(O)C2=C(C=C1)C(=O)C13OC1(C(O)CC1(O)CC(C)=CC(=O)C31O)C2O |
| Description | Antibiotic. Bacterial DNA gyrase inhibitor: Staphylococcus aureus (IC50= 1.45µM), E. coli (IC50= 0.41µM). Human topoisomerase II (Topo II) inhibitor (IC50= 100µM). Antibacterial (Gram-positive). Antitumor compound. |