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TXNDC5 Polyclonal Antibody, PE-Cy5.5 Conjugated

Applications

  • WB

Predicted Reactivity

  • Human
  • Mouse
  • Rat
  • Dog
  • Pig
  • Rabbit
Overview
Catalog # bs-7579R-PE-Cy5.5-100uL
Product Name TXNDC5 Polyclonal Antibody, PE-Cy5.5 Conjugated
Applications
WB
Predicted Reactivity Human, Mouse, Rat, Dog, Pig, Rabbit
Specifications
Conjugation PE-Cy5.5
Host Rabbit
Source KLH conjugated synthetic peptide derived from human TXNDC5
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 81567
Subcellular location Cytoplasm
Synonyms EndoPDI; Endoplasmic reticulum protein ERp46; Endothelial protein disulphide isomerase; ERP46; Hcc 2; PDIA15; Protein disulfide isomerase family A member 15; Thioredoxin domain containing 5 endoplasmic reticulum; thioredoxin domain containing 5; Thioredoxin domain containing protein 5; Thioredoxin like protein p46; Thioredoxin related protein; Thioredoxin-like protein p46; TLP46; TXN5; TXNDC 5; UNQ364; TXND5_HUMAN.
Background TXNDC5 is a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. ERp19 and ERp46 are two newly discovered ER luminal proteins, related to protein disulphide isomerase. Western and Northern blot analyses have revealed that both ERp19 and ERp46 and their respective mRNAs are highly expressed in the liver as compared with other tissues. Both proteins are enriched in purified liver ER vesicles and were localized specifically to the ER in McA-RH7777 hepatocytes. See Knoblach et al. for details.
Application Dilution
WB 1:300-5000

Frequently asked questions

Which applications is TXNDC5 Polyclonal Antibody, PE-Cy5.5 Conjugated (BS-7579R-PE-CY5-5) validated for, and at what dilution?

BS-7579R-PE-CY5-5 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

How should BS-7579R-PE-CY5-5 be stored?

Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise TXNDC5 Polyclonal Antibody, PE-Cy5.5 Conjugated (BS-7579R-PE-CY5-5)?

KLH conjugated synthetic peptide derived from human TXNDC5

What are the excitation and emission wavelengths of the PE-Cy5.5 conjugate (BS-7579R-PE-CY5-5)?

PE-Cy5.5 on BS-7579R-PE-CY5-5: excitation / emission 488nm/694nm.

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