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Blood Group Antigen Precursor Antibody

Applications

  • ELISA
  • IHC-P
  • IHC-F
  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Reactivity

  • Human

Predicted Reactivity

  • Chimpanzee
Overview
Catalog # bs-7589R
Product Name Blood Group Antigen Precursor Antibody
Applications ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity Human
Predicted Reactivity Chimpanzee
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Blood Group Antigen Precursor
Immunogen Range 51-150/354
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 28
Subcellular location Cytoplasm, Secreted, Cell membrane
Synonyms A transferase; Abo; ABO blood group transferase A alpha 1-3 N acetylgalactosaminyltransferase transferase B alpha 1 3 galactosyltransferase; ABO glycosyltransferase; B A alpha 1, 3 glactosyltransferase; B transferase; BGAT_HUMAN; Fucosylglycoprotein 3 alpha galactosyltransferase; Fucosylglycoprotein 3-alpha-galactosyltransferase; Fucosylglycoprotein alpha N acetylgalactosaminyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form; Glycoprotein fucosylgalactoside alpha galactosyltransferase; Glycoprotein fucosylgalactoside alpha N acetylgalactosaminyltransferase; Glycoprotein-fucosylgalactoside alpha-galactosyltransferase; Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase; GTB; Histo blood group A transferase; Histo blood group A2 transferase; Histo blood group ABO system transferase; Histo blood group B transferase; Histo-blood group A transferase; Histo-blood group B transferase; NAGAT.
Background This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene.
Application Dilution
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200