Biocytine
| Overview | |
| Catalog # | bs-75971c-100mg |
| Product Name | Biocytine |
| Specifications | |
| Storage Buffer | Powder |
| Storage Condition | Stable for 2 years after receipt when stored at -20°C. |
| Target | |
| Product Information | CAS Number: 576-19-2 Molecular formula: C16H28N4O4S Molecular weight: 372.48 Purity: >95% (NMR) Appearance: White to off-white powder. Solubility: Soluble in PBS or water (20 mg/ml). We do not recommend to store aqueous solutions for more than one day. InChiKey: BAQMYDQNMFBZNA-WBGPXRNDSA-N SMILES: [H][C@]12CS[C@@H](CCCCC(NCCCCC(N)C(O)=O)=O)[C@@]1([H])NC(N2)=O |
| Description | Biocytin is a conjugate of biotin and lysine known formally as epsilon-N-(d-biotinyl)-L-lysine. The addition of lysine to biotin increases the chain length extending from biotin, allowing the synthesis of medium-chain reagents. It also provides terminal carboxyl and amino groups for derivatization or conjugation to proteins and other molecules. Covalent linking reactions typically involve carbodiimide or NHS-ester crosslinking chemistries. Biocytin is also used as an anterograde, retrograde, or intracellular neuroanatomical tracer that is fixable with aldehyde-based fixatives. It is also used in biotinidase assays. Biocytin may be injected into brain by iontophoresis or by pressure injection methods, and localized in tissue sections using avidin-conjugated labels. |