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5,5'-Difluoro BAPTA-AM

Overview
Catalog # bs-75974c-10mg
Product Name 5,5'-Difluoro BAPTA-AM
Specifications
Storage Buffer Powder
Storage Condition Stable for 2 years after receipt when stored at -20°C.
Target
Product Information CAS Number: 128255-42-5

Molecular formula: C34H38F2N2O18

Molecular weight: 800.66

Purity: >97% (HPLC)

Appearance: White to off-white crystalline powder.

Solubility: Soluble in DMSO, DMF, EtOAc or CHCl3.

InChiKey: ZXXWTKAFGAXGHZ-UHFFFAOYSA-N

SMILES: O=C(OCOC(C)=O)CN(CC(OCOC(C)=O)=O)C1=CC=C(F)C=C1OCCOC2=CC(F)=CC=C2N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O
Description 5,5′-Difluoro-BAPTA-AM is a calcium chelator that may be used to modulate calcium levels and flow within cells to study calcium homeostasis and cell signaling. It is used to study cytosolic free Ca2+ by 19F-NMR. It has high selectivity for Ca2+, it is not particularly pH sensitive and is available protected as its acetoxymethyl ester. Determination with 5,5′-Difluoro-BAPTA-AM are not sensitive to cells which have a high natural background fluorescence.