Calycosin

Overview
Catalog #	bs-76082c-10mg
Product Name	Calycosin
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at +4°C.
Target
Product Information	CAS Number: 20575-57-9 Molecular formula: C16H12O5 Molecular weight: 284.26 Purity: >98% (HPLC) Appearance: White to light yellow powder. Solubility: Soluble in DMSO (20mg/ml), DMF (20mg/ml) or methanol (1mg/ml). InChiKey: QAGGICSUEVNSGH-UHFFFAOYSA-N SMILES: O=C1C=C(C2=CC=C(OC)C(O)=C2)OC3=CC(O)=CC=C31
Description	Calycosin is an isoflavone and phytoestrogen with diverse biological properties, including anti-cancer, anti-inflammatory, antioxidant, neuroprotective, antiplasmodial and antiprotozoal activities. It is an estrogen receptor (ER) partial agonist that inhibits 17beta-estradiol binding to ERalpha and ER, promotion angiogenesis. It has been shown to have calcium blocking activities. Suppressed breast cancer cell growth via ER?-dependent regulation of IGF-1R, p38 MAPK and PI3K/Akt pathways. Shown to induce apoptosis in several cancer types and having antimetastatic and anti-tumor activities.