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Clomiphene citrate

Overview
Catalog # bs-76091c-1g
Product Name Clomiphene citrate
Specifications
Storage Buffer Solid
Storage Condition Stable for 2 years after receipt when stored at +4°C.
Target
Product Information CAS Number: 50-41-9

Molecular formula: C26H28ClNO . C6H8O7

Molecular weight: 598.08

Purity: >98% (HPLC)

Appearance: Solid.

Solubility: Soluble in DMOS or DMF. Slightly soluble in water, methanol or chloroform.

InChiKey: PYTMYKVIJXPNBD-BTKVJIOYSA-N

SMILES: Cl/C(C1=CC=CC=C1)=C(C2=CC=CC=C2)/C3=CC=C(OCCN(CC)CC)C=C3.OC(CC(C(O)=O)(O)CC(O)=O)=O

SMILES: OC(=O)CC(O)(CC(O)=O)C(O)=O.CCN(CC)CCOC1=CC=C(C=C1)C(=C(Cl)C1=CC=CC=C1)C1=CC=CC=C1
Description Clomiphene is a nonsteroidal triphenylethylene derivative. It acts as a selective estrogen receptor modulator (SERM), that impairs the activation of estrogen receptors (ERs) by 17beta-estradiol, similar to tamoxifen and raloxifene. It potently binds both ERalpha and ERbeta (Ki = 0.9 and 1.2nM, respectively). Clomiphene enhances the release of gonadotropin-releasing hormone, stimulating the release of follicle-stimulating hormone and luteinizing hormone, culminating in ovulation. Triphenylethylene antiestrogens may also be used as antileukemic drugs which kill cells by apoptosis mediated by oxidative stress and activation of PKC.

Frequently asked questions

Which applications is Clomiphene citrate (bs-76091C) validated for, and at what dilution?

bs-76091C is validated for Life Science( N/A).

How should bs-76091C be stored?

Stable for 2 years after receipt when stored at +4°C. Storage buffer: Solid