Cnidicin

Overview
Catalog #	bs-76098c-1mg
Product Name	Cnidicin
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 14348-21-1 Molecular formula: C21H22O5 Molecular weight: 354.4 Purity: >98% (HPLC) Appearance: Light yellow powder. Solubility: Soluble in DMSO. InChiKey: HJMDOAWWVCOEDW-UHFFFAOYSA-N SMILES: C/C(C)=C/COC1=C2C(OC(C=C2)=O)=C(OC/C=C(C)/C)C3=C1C=CO3
Description	Cnidicin is a natural product isolated from the root extract of Angelica koreana (Umbelliferae). Cnidicin has anti-allergic and anti-inflammatory activity. It inhibits the degranulation of mast cell and the nitric oxide (NO) generation in RAW 264.7 cells, by inhibition of nitric oxide synthase expression. Cnidicin has shown anti-proliferative and cytotoxic activity in vitro on cultured human tumor cells such as A549 (non small cell lung), SK-OV-3 (ovary), SK-MEL-2 (melanoma), XF498 (central nervous system) and HCT-15 (colon).