DPM

Overview
Catalog #	bs-76129c-25mg
Product Name	DPM
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 143503-03-1 Molecular formula: C20H16N2O5 Molecular weight: 364.35 Purity: >97% (HPLC) Appearance: Solid. Solubility: Soluble in DMSO. InChiKey: ISCHQGBNSNVWCQ-UHFFFAOYSA-N SMILES: COC1=C(OC)C=C2C(CN(C2=O)C2=CC=C(C=C2)N2C(=O)C=CC2=O)=C1 SMILES: COC1=C(OC)C=C2C(CN(C2=O)C2=CC=C(C=C2)N2C(=O)C=CC2=O)=C1
Description	Nonfluorescent N-substituted maleimides react selectively with thiol compounds to form fluorescent derivatives. Fluorescent intensity of the dimethoxyphthalimidyl group is higher than that of the nonsubsituted phthalimidyl group. The analytical sensitivity of N-[4-(5,6-Dimethoxy-N-phthalimidyl)phenyl]maleimide (DPM) is about 3-times higher than that of N-[4-(2-phthalimidyl)phenyl]maleimide (PPM). DPM can be used as a precolumn labeling reagent in HPLC. DPM was also used for the determination of physiologically important thiols in biological fluids or therapeutic drug monitoring.