Dihydrofluorescein diacetate

Overview
Catalog #	bs-76151c-1g
Product Name	Dihydrofluorescein diacetate
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 35340-49-9 Molecular formula: C24H18O7 Molecular weight: 418.4 Purity: >97% (NMR) Appearance: Solid. Solubility: Soluble in chloroform. InChiKey: YKSJJXGQHSESKB-UHFFFAOYSA-N SMILES: CC(=O)OC1=CC2=C(C=C1)C(C1=C(O2)C=C(OC(C)=O)C=C1)C1=C(C=CC=C1)C(O)=O SMILES: CC(=O)OC1=CC2=C(C=C1)C(C1=CC=CC=C1C(O)=O)C1=C(O2)C=C(OC(C)=O)C=C1
Description	Dihydrofluorescein diacetate is a fluorescent probe for detecting intracellular oxidants. It is hydrolyzed by cellular esterases to dihydrofluorescein and is then oxidized to fluorescein primarily by H2O2. Dihydrofluorescein diacetate might be reactive toward a broad range of oxidizing reactions that may be increased during intracellular oxidant stress. Cell-loading studies indicate that dihydrofluorescein achieves higher intracellular concentrations than the other redox sensors such as Dihydrorhodamine 123 (Ex/Em: 490/514nm).