Overview |
bs-7618R-Biotin |
NOC2L Polyclonal Antibody, Biotin Conjugated |
ELISA, IHC-P, IHC-F |
Human, Mouse, Rat, Cow, Sheep, Pig |
Specifications |
Biotin |
Rabbit |
KLH conjugated synthetic peptide derived from human NOC2L |
251-350/749 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
26155 |
Cytoplasm, Nucleus |
NIR; NOC2 like; Novel INHAT inhibitor of histone acetyltransferase repressor; Nucleolar complex associated 2 homolog S. cerevisiae; Protein NOC2 homolog; NOC2L_HUMAN. |
NOC2L is a transcriptional corepressor with inhibitor of histone acetyltransferase (INHAT) activity. NOC2L or NIR (Novel INHAT Repressor) is ubiquitously expressed throughout embryonic development and adulthood. It is a potent transcriptional corepressor that is not blocked by histone deacetylase inhibitors and is capable of silencing both basal and activator-driven transcription. NOC2L directly binds to nucleosomes and core histones and prevents acetylation by histone acetyltransferases, thus acting as a bona fide INHAT. |
Application Dilution |
ELISA |
1:500-1000 |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |