Glycochenodeoxycholic acid sodium salt

Overview
Catalog #	bs-76351c-500mg
Product Name	Glycochenodeoxycholic acid sodium salt
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 16564-43-5 Molecular formula: C26H42NNaO5 Molecular weight: 471.61 Purity: >97% (HPLC) Appearance: White to off-white powder. Solubility: Slightly soluble in DMSO, ethanol or methanol (10mg/ml) and in water. InChiKey: AAYACJGHNRIFCT-YRJJIGPTSA-M SMILES: [H][C@]1([C@@H](CCC(NCC(O[Na])=O)=O)C)CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C SMILES: [Na+].C[C@H](CCC(=O)NCC([O-])=O)[C@H]1CC[C@H]2[C@@H]3C(O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
Description	Glycochenodeoxycholic acid (GCDCA) is a bile salt formed in the liver that acts as a biosurfactant to solubilize lipids for absorption and is itself absorbed. GCDCA functions as a choleretic, increasing the volume of bile secreted from the liver, and a cholagogue, promoting the discharge of bile from the digestive system. GCDCA has been used to demonstrate a role for bile acids in promoting colorectal carcinogenesis and to inhibit calcium hydroxyapatite precipitation to study the pathogenesis of black pigment gallstones. This product has also been shown to induce apoptosis in isolated hepatocytes via modulation of PKC activity. This compound is used as an anionic detergent to solubilize lipids and as a chiral reagent.