Glucuronolactone

Overview
Catalog #	bs-76356c-25g
Product Name	Glucuronolactone
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at +20°C.
Target
Product Information	CAS Number: 32449-92-6 Molecular formula: C6H8O6 Molecular weight: 176.12 Purity: >98% (HPLC) Appearance: White powder. Solubility: Soluble in water. InChiKey: OGLCQHRZUSEXNB-VGASXLIASA-N SMILES: O[C@@H]1[C@@H](OC2=O)[C@@H]([C@@H]2O)OC1O SMILES: O[C@@H]1O[C@@H]2[C@@H](O)C(=O)O[C@@H]2[C@H]1O
Description	Naturally occurring carbohydrate derivative that is an important structural component of nearly all connective tissues and is also found in many plant gums. Metabolized to glucaric acid, xylitol, and L-xylulose, and humans may also be able to use glucuronolactone as a precursor for ascorbic acid synthesis. Used as a detoxicant. The liver uses glucose to create glucuronolactone, which inhibits the enzyme B-glucuronidase (metabolizes glucuronides), which should cause blood-glucuronide levels to rise. Glucuronides combine with toxic substances, such as morphine and depot medroxyprogesterone acetate, by converting them to water-soluble glucuronide-conjugates which are excreted in the urine. Used as building block and starting reagent for synthesis of drugs, optically active glucopyranoses and long-chain alkyl glucofuranosides.