Levocetirizine dihydrochloride

Overview
Catalog #	bs-76487c-10mg
Product Name	Levocetirizine dihydrochloride
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 2 years after receipt when stored at RT.
Target
Product Information	CAS Number: 130018-87-0 Molecular formula: C21H25ClN2O3 . 2HCl Molecular weight: 461.81 Purity: >98% (HPLC) Appearance: Solid. Solubility: Soluble in water (20mg/ml). InChiKey: PGLIUCLTXOYQMV-GHVWMZMZSA-N SMILES: ClC(C=C1)=CC=C1[C@@H](C2=CC=CC=C2)[NH+]3CC[NH+](CCOCC(O)=O)CC3.[Cl-].[Cl-] SMILES: Cl.Cl.OC(=O)COCCN1CCN(CC1)[C@H](C1=CC=CC=C1)C1=CC=C(Cl)C=C1
Description	Levocetirizine hydrochloride is the (R)-enantiomer of the histamine H1 receptor antagonist and antihistamine agent cetirizine. It binds to the H1 receptor with higher affinity than cetirizine and is 25,000-100,000-fold selective for H1 receptors over muscarinic M1-M5 receptors. Intranasal administration dose-dependently decreases histamine-induced nasal rubbing and sneezing in mice. Has been used in the treatment of allergic rhinitis and chronic idiopathic urticaria.