(±)-Naringenin

Overview
Catalog #	bs-76608c-5g
Product Name	(±)-Naringenin
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at +4°C.
Target
Product Information	CAS Number: 67604-48-2 Molecular formula: C15H12O5 Molecular weight: 272.25 Purity: >98% (HPLC) Appearance: Off-white to beige powder. Solubility: Soluble in DMSO (5mg/ml), DMF (10mg/ml) or ethanol (2mg/ml). InChiKey: FTVWIRXFELQLPI-UHFFFAOYSA-N SMILES: OC1=CC(O)=C2C(OC(C3=CC=C(O)C=C3)CC2=O)=C1 SMILES: OC1=CC=C(C=C1)C1CC(=O)C2=C(O1)C=C(O)C=C2O
Description	Naringenin is a citrus-derived flavonoid that inhibits CYP3A4 activity in human liver microsomes. It has a broad panel of properties, including antibacterial, antiviral, antifungal, anti-inflammatory, antioxidant, anticancer, antidiabetic, cardioprotective and neuroprotective activities. Naringenin activity is primarily attributed to its anti-inflammatory (via inhibiting recruitment of cytokines and inflammatory transcription factors) and antioxidant (via scavenging of free radicals, bolstering of endogenous antioxidant defense system and metal ion chelation) effects. Naringenin exerts its anti-diabetic effects by inhibition of gluconeogenesis through upregulations of AMPK, leading to its lipid lowering and insulin-like properties.