MDMX Polyclonal Antibody, PE-Cy5.5 Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-7663R-PE-Cy5.5-100uL |
| Product Name | MDMX Polyclonal Antibody, PE-Cy5.5 Conjugated |
| Applications |
WB
|
| Reactivity | Mouse |
| Predicted Reactivity | Human, Rat, Dog, Cow, Sheep, Pig, Horse, Rabbit |
| Specifications | |
| Conjugation | PE-Cy5.5 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human MDM4 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 4194 |
| Swiss Prot | O15151 |
| Subcellular location | Nucleus |
| Synonyms | HDMX; MDMX; MRP1; Protein Mdm4; Double minute 4 protein; Mdm2-like p53-binding protein; Protein Mdmx; p53-binding protein Mdm4; MDM4 |
| Background | Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions. |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is MDMX Polyclonal Antibody, PE-Cy5.5 Conjugated (BS-7663R-PE-CY5-5) validated for, and at what dilution?
BS-7663R-PE-CY5-5 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does MDMX Polyclonal Antibody, PE-Cy5.5 Conjugated (BS-7663R-PE-CY5-5) react with?
Tested reactivity: Mouse. Predicted reactivity (expected from sequence homology but not yet tested): Human, Rat, Dog, Cow, Sheep, Pig, Horse, Rabbit.
How should BS-7663R-PE-CY5-5 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise MDMX Polyclonal Antibody, PE-Cy5.5 Conjugated (BS-7663R-PE-CY5-5)?
KLH conjugated synthetic peptide derived from human MDM4
What are the excitation and emission wavelengths of the PE-Cy5.5 conjugate (BS-7663R-PE-CY5-5)?
PE-Cy5.5 on BS-7663R-PE-CY5-5: excitation / emission 488nm/694nm.