Quinidine anhydrous

Overview
Catalog #	bs-76744c-10g
Product Name	Quinidine anhydrous
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at RT.
Target
Product Information	CAS Number: 56-54-2 Molecular formula: C20H24N2O2 Molecular weight: 324.42 Purity: >99% (Titr.) Appearance: White to faint yellow powder. Solubility: Soluble in DMSO (20mg/ml) or ethanol (5mg/ml). InChiKey: LOUPRKONTZGTKE-LHHVKLHASA-N SMILES: O[C@@H](C1=C(C=C(OC)C=C2)C2=NC=C1)[C@]3([H])[N@](C[C@@H]4C=C)CC[C@@]4([H])C3
Description	Quinidine is a dextrorotatory stereoisomer of Quinine with anti-malarial, anti-arrhythmic (class 1A), anti-inflammatory, anti-cancer and anti-viral properties. Quinidine acts as a blocker of voltage-gated sodium channels. Inhibition of the Nav1.5 channel is specifically involved in its anti-arrhythmic effects as a class I anti-arrhythmic agent. Quinidine also blocks certain voltage-gated potassium channels (e.g. Kv1.4, Kv4.2, hERG, among others), acts as an anti-muscarinic. Quinidine blocks alpha1-adrenoceptors (alpha1ARs) and is an inhibitor of cytochrome P450 and acetylcholinesterase.