RBM38 Polyclonal Antibody, RBITC Conjugated
Applications
Predicted Reactivity
| Overview | |
| Catalog # | bs-7682R-RBITC-100uL |
| Product Name | RBM38 Polyclonal Antibody, RBITC Conjugated |
| Applications |
IF(IHC-P)
IF(IHC-F)
IF(ICC)
|
| Predicted Reactivity | Human, Mouse, Rat, Dog, Cow, Pig, Chicken, Rabbit |
| Specifications | |
| Conjugation | RBITC |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human RBM38 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 55544 |
| Subcellular location | Cytoplasm, Nucleus |
| Synonyms | SEB4D; CLL associated antigen KW 5; CLL-associated antigen KW-5; HSRNASEB; RBM38; RBM38_HUMAN; RNA binding mot protein 38; RNA binding protein 38; RNA binding region RNP1, RRM containing 1; RNA binding region containing protein 1; RNA-binding mot protein 38; RNA-binding protein 38; RNA-binding region-containing protein 1; RNPC1; SEB4; SEB4B; ssDNA binding protein SEB4; ssDNA-binding protein SEB4. |
| Background | RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation. |
| Application Dilution | |
| IF(IHC-P) | 1:50-200 |
| IF(IHC-F) | 1:50-200 |
| IF(ICC) | 1:50-200 |
Frequently asked questions
Which applications is RBM38 Polyclonal Antibody, RBITC Conjugated (bs-7682R-RBITC) validated for, and at what dilution?
bs-7682R-RBITC is validated for IF(IHC-P) (1:50-200); IF(IHC-F) (1:50-200); IF(ICC) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
How should bs-7682R-RBITC be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise RBM38 Polyclonal Antibody, RBITC Conjugated (bs-7682R-RBITC)?
KLH conjugated synthetic peptide derived from human RBM38
What are the excitation and emission wavelengths of the RBITC conjugate (bs-7682R-RBITC)?
RBITC on bs-7682R-RBITC: excitation / emission 540nm/625nm.