Umbelliferon

Overview
Catalog #	bs-76875c-25g
Product Name	Umbelliferon
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 2 years after receipt when stored at +4°C.
Target
Product Information	CAS Number: 93-35-6 Molecular formula: C9H6O3 Molecular weight: 162.14 Purity: >98% (NMR) Appearance: Beige solid. Solubility: Soluble in DMSO (10mg/ml), ethanol (5 mg/ml), methanol (5 mg/ml) or dioxane. InChiKey: ORHBXUUXSCNDEV-UHFFFAOYSA-N SMILES: O=C1OC2=CC(O)=CC=C2C=C1 SMILES: OC1=CC=C2C=CC(=O)OC2=C1
Description	Umbelliferone is a naturally occurring derivative and metabolite of coumarin that has diverse biological activities including antitumor, antioxidant, antihyperglycemic, anti-inflammatory, neuroprotective and antidepressant-like properties. It inhibits the growth of a variety of human cell lines. It increases the production of reactive oxygen species (ROS), depolarizes the mitochondrial membrane, and halts the cell cycle at the G0/G1 phase in KB human oral carcinoma cells. Umbelliferone has been used as a ratiometric pH indicator. Spectral Data: Em=460nm / Ex=330(ph<6)/370nm(pH>8). Umbelliferone can also be used as building block to synthesize fluorescent probes or biochemically active APIs.